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KMID : 0950020060320010041
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Journal of Health Science & Medical Technology
2006 Volume.32 No. 1 p.41 ~ p.46
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Studies on the Cytoglobin of Human Leukocyte
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Kim Jin-Kwan
Shin Chol
Lee Seung-Gwan
Lee Chang-Kyu
Kim Sung-Wook
Jo Kyung-Jin
Kim Soon-Ki
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Abstract
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Cytoglobin(Cygb) is a newly recognized globin type, which are almost ubiquitously present in human tissues. Cytoglobin is reported to function as an oxygen scavanging and distribution protein and induced by hypoxia. The physiological role of cytoglobin is not yet clearly understood. We investigated cytoglobin in human blood leukocyte from obstructive sleep apnea patients(n=5) and normal controls(n=5). Immunoreactivity to anticytoglobin in OSA patients were much higher than that in normal control. These results suggest that cytoglobins of leukocyte might be overexpressed in obstructive sleep apnea.
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KEYWORD
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Cytoglobin, Leulocyte, Obstructive Sleep Apnea
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